Huntington's News

How disordered proteins spread from cell to cell, potentially spreading disease

Posted: 24th February 2011

One bad apple is all it takes to spoil the barrel. And one misfolded protein may be all that's necessary to corrupt other proteins, forming large aggregations linked to several incurable neurodegenerative diseases such as Huntington's, Parkinson's and Alzheimer's.

Stanford biology Professor Ron Kopito has shown that the mutant, misfolded protein responsible for Huntington's disease can move from cell to cell, recruiting normal proteins and forming aggregations in each cell it visits.

Read more on EurekAlert.

Collaboration to advance therapy for Huntington’s Disease

Posted: 28th January 2011

UMass Medical School has entered into a research collaboration with pharmaceutical company Lundbeck Inc. aimed at further development of a targeted therapy to slow or halt the progression of Huntington’s disease (HD).

Read the full story at EurekAlert.

Genetic research offers hope of improved treatment for Huntington's disease

Posted: 27th January 2011

Research led by the University of Leicester in the UK has raised hopes about possible new treatments for devastating neurodegenerative disorders such as Huntington's disease, for which there is currently no cure. The trans-Atlantic team of scientists made the discoveries using cutting-edge genetic techniques. The study was partially funded by a Marie Curie grant under the EU's Seventh Framework Programme (FP7), and has been published in The Journal of Biological Chemistry.

Read more at the European Commission CORDIS website.

Four UBC professors appointed to the Order of Canada

Posted: 9th January 2011

Four professors and three members of the UBC community have been named to the Order of Canada, one of Canada’s highest civilian honours. The Order of Canada recognizes a lifetime of achievement and contribution to society.

Dr. Michael Hayden, a professor in the departments of medicine and medical genetics at UBC and the director of the Centre for Molecular Medicine and Therapeutics at the Child and Family Research Institute, was appointed a Member of the Order of Canada. This honour recognizes Dr. Hayden’s contribution to our understanding of Huntington’s disease and other genetic disorders.

Read the full story at the website of the University of British Columbia.

We have a new name!

Posted: 6th January 2011

Huntington's New South Wales is the trading name of the Australian Huntington's Disease Association (NSW) Inc., which remains our incorporation name. This name change was adopted by members at the recent AGM and follows recent name changes to the other state associations and to the national association.

All our contact and other details remain the same.

Huntington's symptoms appear a decade before diagnosis

Posted: 4th December 2010

People with Huntington's disease show symptoms more than a decade before they are likely to get a clinical diagnosis. These early effects of the disease don't affect day-to-day functioning, but they will help drug developers evaluate treatments that target the early stages of the disease.

Read more about this Australian research on the New Scientist website.

Fighting Huntington's disease brings together Cleveland researchers from several fields

Posted: 2nd June 2010

A rare meeting of some of the brightest investigators involved in local brain, genetics and cancer research took place over a 48-hour period recently in Cleveland, a collaboration that Case Western Reserve University pathologist Alan Tartakoff hopes will make the city a hub for research into Huntington's disease.

Read the full story on Cleveland.com

Faulty Clean-Up Process May Be Key Event in Huntington's Disease

Posted: 31st May 2010

ScienceDaily (Apr. 25, 2010) — In a step towards a possible treatment for Huntington's disease, scientists at Albert Einstein College of Medicine of Yeshiva University have shown for the first time that the accumulation of a mutated protein may explain damaging cellular behavior in Huntington's disease. Their research is described in the April 11 online edition of Nature Neuroscience.

Read more on the ScienceDaily website.

Staying active delays Huntington's disease

Posted: 29th May 2010

Melbourne researchers have made a breakthrough in the research into Huntington's disease, a genetic condition that inevitably leads to dementia and a shorter life. In a world-first study, scientists have found that leading a more active lifestyle can delay the onset of symptoms.

Read the full story on the ABC News website.

Do-It-Yourself Genetic Tests

Posted: 27th May 2010

LONDON – If you were hoping to pick up a DNA kit along with your shampoo from the drugstore, you would be out of luck. The United States Food and Drug Administration recently warned the giant pharmacy chain Walgreen’s to think twice before stocking personal genetic testing kits. As an FDA spokeswoman said, "These kits have not been proven safe, effective or accurate, and patients could be making medical decisions based on data from a test that hasn’t been validated by the FDA."

Read more at the Project Syndicate website.

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